Figure 2.

The inflammatory difference between the right and left eyes after iPSC-RPE transplantation. The eyes of monkey HM-1 were histologically examined. (A,B) H&E staining of the right (A) and left (B) eye. Graft cells are indicated by the red dot-line. The mass of inflammatory cells is indicated by the yellow dot-line. The left eye exhibited severe inflammation compared to the right eye. Scale bars: 50 μm. (C,D) IHC of the right (C) and left (D) eye. A larger amount of CD3⁺ infiltration (green) was detected in the left eye compared to the right eye. PKH-positive live grafted RPE cells (red) were not detected. Scale bars: 20 μm. CHO: choroid.