Table 2.
TLR-4 | |||
---|---|---|---|
Types of Cells | PAMPs | DAMPs | Clinical-Trial Agent Characteristics |
Monocytes Macrophages Neutrophil Myeloid dendritic cells Mast cells B cells Intestinal epithelium Platelets |
Lipopolysaccharide | HSPs, heparin, fibrinogen, fibronectin, sulfate, HMGB1, ANG II |
Anti-TLR-4 antibody, lipid A derivates, polysaccharides. |