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. 2020 Apr 28;21(9):3097. doi: 10.3390/ijms21093097

Figure 5.

Figure 5

Inhibition of endotoxin-stimulated MV-induced lung injury in HIF-1α deficient mice. (A) Lung wet-to-dry-weight ratio, (B) BAL fluid total protein, (C) IL-6, (D) TNF-α, (E) MIP-2 and (F) VEGF secretion in BAL fluid, (G) MPO activity, (H) protein carbonyl groups and (I) SOD were from the lungs of nonventilated control mice and those subjected to a tidal volume of 30 mL/kg for 5 h with LPS administration (n = 5 per group). * p < 0.05 versus the nonventilated control mice with LPS; † p < 0.05 versus HIF-1α-deficient mice. HIF−/− = hypoxia inducible factor-1α-deficient mice.