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. 2020 Apr 28;21(9):3098. doi: 10.3390/ijms21093098

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Histopathological comparison of both treated and HF-treated membranes. Images of Masson-Goldner (C,D) and Von Kossa (A,B,E,F) staining of the implantation site at 6, 12 and 18 weeks (100× magnifications, scalebars = 100 µm). Left for untreated (Mg) and right for HF-treated (Mg^#) magnesium. Mg is mainly degraded via dissolution and scarcely through phagocytic processes. Mg-HF however, is primarily being resorbed via active phagocytosis and non-cellular dissolution only plays a minor role. After degradation of the HF-coating, decomposition, as with untreated Mg, principally occurs non-cellular-driven but through dissolution. Yellow arrows = phagocytic cells, black arrows = fibroblasts, asterisks = slight fibrosis, white arrows = septa between the gas cavities.