Figure 2.

Effect of BME (50 mg/kg) on spatial working memory in 5-week-old and 8-week-old mice after 7 days of treatment. Spatial working memory was elucidated by the modified Y-maze test. Red arrows indicate the day behavioral tests were conducted. Summarized data obtained on 5-week-old mice (A) and 8-week-old mice (B) after 7 days BME treatment; 5-week-old mice received daily BME at a dose of 50 mg/g (p.o.) for 7 days, and then the spatial working memory was evaluated at 28 days after the last drug administration (C). Results are expressed as % of the time animals spent exploring the novel arm in the test trial. Each data column represents the mean ± SEM (n = 10–12). ** p < 0.01; * p < 0.05 vs. the control group.