Table 3.
Exploratory Whole-Brain Analyses on Age Group Interactions of Associations Between Sleepiness (KSS Scores) and GM Volume
| Region | Age Effect | MNI (x, y, z) | Z | Voxels (mm3) | P(Uncorr) |
|---|---|---|---|---|---|
| R thalamus | Interaction Y+ O– | 20, –26, 4 | 4.60 | 1485 | <.001 |
| R insula | Interaction Y+ O– | 32, 8, –18 | 4.35 | 1593 | <.001 |
| L insula | Interaction Y+ O– | –34, 8, –16 | 4.28 | 2228 | <.001 |
| R insula | Interaction Y+ O– | 44, 16, –6 | 4.09 | 378 | <.001 |
| L cerebellum | Interaction Y+ O– | –18, –74, –48 | 4.01 | 1529 | <.001 |
| R cerebellum | Interaction Y+ O– | 46, –74 –32 | 3.83 | 1232 | <.001 |
| L thalamus | Interaction Y+ O– | –15, –22, 2 | 3.75 | 270 | <.001 |
| R postcentral | Interaction Y+ O– | 39, –34, 58 | 3.60 | 250 | <.001 |
| R cerebellum | Interaction Y+ O– | 8, –48, –36 | 3.36 | 95 | <.001 |
| L parietal superior | Interaction Y+ O– | –27, –62, 44 | 3.36 | 139 | <.001 |
| R cerebellum | Interaction Y+ O– | 26, –78, –54 | 3.32 | 422 | <.001 |
Notes: Y+ indicates positive association in younger adults, and O– indicatesnegative association in older adults.
Abbreviations: GM, gray matter; MNI, Montreal Neurological Institute; L, left; R, right; KSS, Karolinska Sleepiness Scale; Uncorr, uncorrected. x, y, z = coordinates.