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. 2020 May 12;11:850. doi: 10.3389/fimmu.2020.00850

Figure 5.

Figure 5

Viral loads, anti-SIV IgG titers and neutralizing antibody response in semen and blood of SIVmac251 infected macaques. Longitudinal follow-up of viral loads, IgG targeting SIV, and neutralizing Ab response in six infected macaques. Each color represents a different animal. (A) Blood and seminal plasma viral RNA loads (BVL: solid lines, SVL: dotted lines) of six macaques infected with 5,000 AID50 IV. (B) Spearman correlation between semen SIV-specific IgG titers and SVL at 51 and 148 dpi. (C) Blood (left panel) and seminal plasma (right panel) titers of SIV-specific IgG for each macaque (the 2 titer values are connected by a line) at baseline and 51 and 148 dpi. (D) Neutralizing antibody response in the blood (left panel) and seminal plasma (right panel) of six infected macaques at 148 dpi. The dotted line represents 50% of viral inhibition. The mean and SEM are shown. *p < 0.05 and **p < 0.01.