Table 3. Comparison between FNA and FNB based on EUS-tissue sampling access.

Transgastric access	Total	FNA	FNB	P value
Sensitivity	85.40 % (95 % CI, 80.11 to 89.73)	84.29 % (95 % CI, 73.62 to 91.89)	87.01 % (95 % CI, 80.66 to 91.88)	0.546
Specificity	97.78 % (95 % CI, 88.23 to 99.94)	100.00 % (95 % CI, 81.47 to 100.00)	96.30 % (95 % CI, 81.03 to 99.91)	0.977
Positive likelihood ratio	38.43 (95 % CI, 5.53 to 267.11)	NA	23.49 (95 % CI, 3.43 to 160.94)	NA
Negative likelihood ratio	0.15 (95 % CI, 0.11 to 0.21)	0.16 (95 % CI, 0.09 to 0.27)	0.13 (95 % CI, 0.09 to 0.20)	0.951
Positive predictive value	99.48 % (95 % CI, 96.52 to 99.93)	100.00 %	99.26 % (95 % CI, 95.14 to 99.89)	0.419
Negative predictive value	57.14 % (95 % CI, 49.23 to 64.70)	62.07 % (95 % CI, 48.75 to 73.79)	56.52 % (95 % CI, 46.18 to 66.33)	0.387
Accuracy	87.45 % (95 % CI, 82.91 to 91.15)	87.50 % (95 % CI, 78.73 to 93.59)	88.40 % (95 % CI, 82.81 to 92.67)	0.831
Transduodenal access
Sensitivity	89.12 % (95 % CI, 84.471 to 92.77)	85.71 % (95 % CI, 75.87 to 92.65)	90.74 % (95 % CI, 85.19 to 94.72)	0.214
Specificity	96.97 % (95 % CI, 84.24 to 99.92)	90.91 % (95 % CI, 58.72 to 99.77)	100.00 % (95 % CI, 84.56 to 100.00)	0.943
Positive likelihood ratio	29.41 (95 % CI, 4.27 to 202.74)	9.43 (95 % CI, 1.45 to 61.24)	NA	NA
Negative likelihood ratio	0.11 (95 % CI, 0.08 to 0.16)	0.16 (95 % CI, 0.09 to 0.28)	0.09 (95 % CI, 0.106 to 0.15)	0.482
Positive predictive value	99.53 % (95 % CI, 96.87 to 99.93)	98.51 % (95 % CI, 91.04 to 99.77)	100.00 %	0.991
Negative predictive value	55.17 % (95 % CI, 46.00 to 64.00)	47.62 % (95 % CI, 33.77 to 61.84)	59.46 % (95 % CI, 47.53 to 70.37)	0.902
Accuracy	90.07 % (95 % CI, 85.89 to 93.36)	86.36 % (95 % CI, 77.39 to 92.75)	91.85 % (95 % CI, 86.91 to 95.37)	0.157

FNA, fine-needle aspiration; FNB, fine-needle biopsy; EUS, endoscopic ultrasound