Table 3:
Minimally-invasive versus Open Approach
| Author | Year | Design | N | Groups | Superior Group | Metric | Global Advantage | Symptom Advantage |
|---|---|---|---|---|---|---|---|---|
| Kim (69) (COACT 0301) |
2008 | RCT | 164 | Lap Open |
LADG | EORTC-C30 STO22 (< 1 year) |
Global (up to 3 mo) | Physical, emotional functioning Dysphagia, diet restrict, dry mouth, body image, reflux, pain |
| Kim (70) (COACT 0301) |
2013 | RCT | 164 | Lap Open |
ND | EORTC-C30 STO22 (> 1 year) |
Dysphagia higher in ODG Dyspnea higher in LADG |
|
| Kobayashi (36) | 2011 | Cohort | 98 | LADG ODG |
LADG | EORTC-C30 STO22 | Global (1 mo) | Physical functioning (up to 12 mo) Fatigue, dyspnea, dysphagia (1-3 mo) |
| Lee (76) | 2012 | Cross-section | 80 | LADG ODG |
ODG | EORTC-C30 STO22 | Role, cognitive functioning Fatigue |
|
| Liu (75) | 2012 | Cohort | 74 | LADG ODG |
LADG | EORTC-C30 STO22 | Role, cogni, emotional function Reflux, body image |
|
| Lee (89) | 2012 | Cohort | 148 | LADG ODG |
LADG | GIQLI | Total | Physical function Post-gastrectomy symptoms |
| Takiguchi (71) | 2013 | RCT | 40 | LADG ODG |
LADG | VAS Activity sensor |
3-day lag in physical activity recup 1-2 day lag in VAS (vis analog scale) |
|
| Woo (90) | 2015 | RCT | 110 | Lap-assist Lap |
ND | EORTC-C30 STO22 | ||
| Misawa (74) | 2015 | Cohort | 145 | Lap Open |
LADG | EORTC-C30 STO22 | Role, emotional, cognitive, social Fatigue, pain, diet retrict, taste, anxiety |
|
| Katai (68) (JCOG0912) |
2017 | RCT | 921 | LADG ODG |
LADG | EORTC-C30 STO22 Analgesics |
Not available | Less analgesia POD 5 |
ND = No difference