Table 3.
Main side effects of DA leading to discontinuation (several possible in the same subject)
PPX-PR (N = 76) | ROP-XL (N = 165) | RTG (N = 183) | ||||
---|---|---|---|---|---|---|
Age range | < 75 years (N = 52) | ≥ 75 years (N = 24) | < 75 years (N = 117) | ≥ 75 years (N = 48) | < 75 years (N = 122) | ≥ 75 years (N = 61) |
Skin reaction (%) | NA | NA | NA | NA | 9.8 | 4.4 |
Lack of effect (%) | 0 | 0 | 1.8 | 0 | 5.5 | 3.8 |
Somnolence (%) | 0 | 1.3 | 1.2 | 0.6 | 0.5 | 0.5 |
Hallucinations (%) | 1.3 | 2.6 | 2.4 | 1.8 | 1.1 | 1.1 |
Confusion (%) | 0 | 1.3 | 1.2 | 0.6 | 0.5 | 1.6 |
ICD (%) | 0 | 2.6 | 3.6 | 1.2 | 1.6 | 0.5 |
PPX-PR pramipexole prolonged release, ROP-XL ropinirole extended release, RTG rotigotine, ICD impulse control disorder, N number, DA dopamine agonists