Fig. 2.

Human adenovirus knob binding to attachment receptors. The trimeric knob is shown in shades of purple, the trimeric fibre shaft is represented by a yellow line (length not to scale). Domains not featured in structures are represented with cartoon shapes. CAR-D1 is bound to HAdV-12, PDB ID: 1KAC [8], CD46 to HAdV-11, PDB ID: 3O8E [39], GD1a to HAdV-37, PDB ID: 3N0I, [11], polySia to HAdV-52, PDB ID: 6G47 and two copies of DSG-2 to HAdV-3, PDB ID: 6QNU