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. 2020 Mar 3;47(7):1757–1768. doi: 10.1007/s00259-020-04736-8

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 7 — Chronic response of brain TSPO signal to enalapril therapy after MI. a Average coronal brain images and b semi-quantification display comparable TSPO signal in brain at 8 weeks after MI with and without enalapril. c In vitro autoradiography confirms globally elevated TSPO signal compared with sham. d Iba1 immunostaining identifies increased microglial content at 8 weeks after MI that remains elevated with enalapril therapy. noTx, untreated; eACE_i, early enalapril treatment; dACE_i, delayed enalapril treatment