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. 2019 Aug 2;35(7):1153–1172. doi: 10.1007/s00467-019-04304-9

Fig. 4.

Fig. 4

Concentration-time profile of antibiotics. Peak/MIC: The ratio of maximum free drug plasma concentration to the MIC. AUC/MIC: The ratio of the total exposure of the drug to the MIC. Time/MIC: The proportion of time that the plasma concentration exceeds the MIC. AUC area under the concentration time curve, Cmax maximum concentration, MIC minimum inhibitory concentration for a pathogen, T time