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Performance of RISK6 signature compared to the ACS 16-gene, Sweeney3 and Maertzdorf4 signatures in GC6-74 non-progressor vs progressor samples, collected within 6 months of TB diagnosis were included.
| GC6-74 progressor vs non-progressor | |||
|---|---|---|---|
| AUC | 95% CI | p | |
| RISK6 | 70.2% | 58.5–81.8% | 0.0002 |
| ACS 16-gene | 67.6% | 60.2–75.0% | <0.0001 |
| Sweeney3 | 71.4% | 61.2–81.7% | <0.0001 |
| Maertzdorf4 | 65.7% | 54.4–77.1% | 0.0003 |
