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. 2020 May 19;14:499. doi: 10.3389/fnins.2020.00499

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Copyright © 2020 Mohammed, Bayford and Demosthenous.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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State transition of PD suppression on feature space of patient/dataset E. (A) Showing PD state transition on a feature space using SVM for state estimation, with “X” markers showing start (from PD) and settling (non-PD) positions. The feature space trajectory is indicated in gray. (B) PD state profile for PD suppression using SVM to obtain state estimates. It depicts the modal interval for the non-PD state when SVM is used for state estimation. (C) Showing PD state transition on a feature space using GMM for state estimation, with “X” markers showing start (from PD) and settling (non-PD) positions. The feature space trajectory is indicated in gray. (D) PD state profile for PD suppression using GMM to obtain state estimates. It depicts the modal interval for the non-PD state when GMM is used for state estimation.