Table 2.
Oncological diseases and antineoplastic treatments.
| cTnI <6 ng/L (n=387) | cTnI 6–40 ng/L (n=63) | cTnI > 40 ng/L (n=35) | NT-proBNP > 125 pg/ml (n=159) | Total cohort (n=485) | |
|---|---|---|---|---|---|
| Oncological disease | |||||
| Breast cancer | 104 (27) | 8 (13) | 6 (17) | 35 (22) | 118 (24) |
| Malignant melanoma | 116 (30) | 11 (17) | 3 (9) | 22 (14) | 130 (27) |
| Multiple myeloma | 23 (6) | 6 (10) | 3 (9) | 13 (8) | 32 (7) |
| Lymphoma | 28 (7) | 2 (3) | 6 (17) | 14 (9) | 36 (7) |
| Leukemia | 39 (10) | 8 (13) | 9 (26) | 24 (15) | 56 (12) |
| Small-cell lung cancer | 13 (3) | 1 (2) | 1 (3) | 5 (3) | 15 (3) |
| Merkel cell carcinoma | 8 (2) | 0 (0) | 4 (11) | 6 (4) | 12 (2) |
| Gastrointestinal cancer | 11 (3) | 3 (5) | 0 (0) | 12 (8) | 14 (3) |
| Antineoplastic treatment | |||||
| Conventional chemotherapy (total) |
243 (63) | 38 (60) | 29 (83) | 117 (74) | 310 (64) |
| Anthracycline | 87 (22) | 13 (21) | 14 (40) | 51 (32) | 114 (24) |
| Alkylation | 148 (38) | 27 (43) | 20 (57) | 59 (37) | 195 (40) |
| Taxane | 61 (16) | 5 (8) | 13 (37) | 11 (7) | 79 (16) |
| Pyrimidine antagonist | 11 (3) | 4 (6) | 3 (9) | 11 (7) | 18 (4) |
| Purine antagonist | 10 (3) | 4 (6) | 1 (3) | 5 (3) | 15 (3) |
| Proteasome inhibitor | 4 (1) | 0 (0) | 3 (9) | 4 (3) | 7 (1) |
| Tyrosine kinase inhibitor | 52 (13) | 9 (14) | 1 (3) | 17 (11) | 62 (13) |
| HER2/neu inhibitor | 24 (6) | 3 (5) | 4 (11) | 15 (9) | 31 (6) |
| PD1 inhibitor | 90 (23) | 9 (14) | 4 (11) | 25 (16) | 103 (21) |
| BRAF inhibitor | 17 (4) | 3 (5) | 1 (3) | 4 (3) | 21 (4) |
| MEK inhibitor | 21 (5) | 2 (3) | 2(6) | 5 (3) | 25 (5) |
| Radiation | 89 (23) | 13 (21) | 5 (14) | 39 (25) | 107 (22) |
| Surgery | 149 (39) | 22 (35) | 10 (29) | 58 (36) | 181 (37) |
Values are presented as the number of patients (percent)
BRAF, B-rapidly growing fibrosarcoma; cTnI, cardiac troponin I; HER2, human epidermal growth factor receptor 2; MEK, mitogen-activated protein kinase; NT-proBNP, N-terminal pro-B-type natriuretic peptide; PD1, programmed cell death protein 1.