Table 1.
Nomenclature of adenoviruses discussed in this review.
| Ad name (this review) | Description (vertebrate species, type) | Species/Group classification | Alternative names reported in the literature |
|---|---|---|---|
| HAdV-B3 | Human adenovirus type 3 | B | Ad3, rAd3 |
| *HAdV-B35 | Human adenovirus type 35 | B | Ad35, rAd35 |
| HAdV-C2 | Human adenovirus type 2 | C | Ad2, rAd2 |
| *HAdV-C5 | Human adenovirus type 5 | C | Ad5, rAd5, AdHu5 |
| *HAdV-C6 | Human adenovirus type 6 | C | Ad6, rAd6, AdHu6 |
| HAdV-D11 | Human adenovirus type 11 | D | Ad11, rAd11 |
| *HAdV-D26 | Human adenovirus type 26 | D | Ad26, rAd26 |
| HAdV-D28 | Human adenovirus type 28 | D | Ad28, rAd28 |
| *HAdV-E4 | Human adenovirus type 4 | E | Ad4, rAd4 |
| ChAdV-1 | Chimpanzee adenovirus type 1 | B2 | ChAd1, AdC1, SAd21 |
| *ChAdV-3 | Chimpanzee adenovirus type 3 | C | ChAd3 |
| ChAdV-7 | Chimpanzee adenovirus type 7 | E | AdC7, ChAd7, SAd24, Pan7 |
| *ChAdV-63 | Chimpanzee adenovirus type 63 | E | ChAd63 |
| ChAdV-68 | Chimpanzee adenovirus type 68 | E | AdC68, ChAd68, SAd25, Pan9, ChAdOx2 |
| *ChAdOx1 | Chimpanzee adenovirus type Y25 | E | Y25 |
| SAdV-11 | Simian adenovirus type 11 | Yet undefined | SAd11, sAd11 |
| SAdV-16 | Simian adenovirus type 16 | Yet undefined | SAd16, sAd16 |
| SAdV-23 | Simian adenovirus type 23 | E | ChAdV-6, AdC6, ChAd6, Pan6 |
| *PanAdV-3 | Pan (paniscus) adenovirus type 3 | C | PanAd3 |
Adenovirus classification for human and non-human Ad vectors referred to in this review. The nomenclature of Ad vectors derived from non-human primates, including chimpanzees, is not standardized, resulting in the confusing use of multiple names assigned by individuals who vectorized these constructs. In this review text, we propose to follow current standards for human Ad vectors, such as HAdV-C5, as outlined by ICTV, for descriptions of Ad vectors derived from chimpanzees or non-human primates. Abbreviated “alternative” names are used in Table 2 due to space constraints. H, human; Ch, chimpanzee; S, simian.
Vectors used in human clinical trial.