Figure 5.

Responding to low-intensity heat stimuli at remote locations of the capsaicin-treated forearm (yellow), close to the border of the capsaicin-treated skin (orange), at the capsaicin-treated skin (red), and at the contralateral forearm (purple). (A) Percentage of non-perceived stimuli in response to low-intensity heat stimuli preferentially activating C-warm afferents [C-warm (38°C)]. (B) Intensity ratings. (C) Reaction times. Graphs represent mean ± SEM. The + indicates significant differences at D1–D7 compared to D0 within one location, ^*indicates significant differences between remote and capsaicin locations, ^#indicates significant difference between border and capsaicin locations, and ° indicates significant differences between the contralateral locations compared to the capsaicin-treated location (+/° ≤ 0.05, ++/°° ≤ 0.01 and ***/+++/###/°°° ≤ 0.001).