Table 1.

Percentage of non-perceived stimuli, intensity ratings, and reaction time latencies at baseline (D0) and statistical analysis of the data-sets by repeated-measures two-way ANOVAs (mixed-effects model), with factors time (four levels: D0, D1, D3, and D7) and location (four levels: remote, border, center, contralateral), using Tukey’s multiple comparisons post-hoc test.

Percentage non-perceived	High-intensity heat (55°C)	Intermediate-intensity heat (44°C)	Low-intensity heat (38°C)	Cool (10°C)
Percentage non-detected at D0
- Capsaicin area	1 ± 1.0%	12 ± 4.0%	13 ± 3.6%	1 ± 0.9%
- Border area	2 ± 1.1%	8 ± 3.1%	14 ± 4.9%	3 ± 1.2%
- Remote area	1 ± 1.0%	14 ± 4.0%	19 ± 4.0%	2 ± 1.2%
- Contralateral area.	0%	11 ± 4.1%	11 ± 6.1%	0%
Main effect of time	F3,60 = 21.7	F3,176 = 38.8	F2,99 = 27.2	F2,134 = 0.5
Main effect of location	F3,60 = 48.6	F3,62 = 20.9	F3,43 = 36.7	F3,62 = 1.1
Time × location interaction	F9,120 = 36.5	F9,186 = 21.7	F9,129 = 11.5	F9,186 = 0.6
Intensity of perception
Intensity of perception at D0
- Capsaicin area	55 ± 3.7	15 ± 2.3	9 ± 1.4	16 ± 1.6
- Border area	52 ± 3.9	15 ± 1.9	10 ± 1.5	15 ± 1.6
- Remote area	52 ± 3.7	13 ± 1.5	8 ± 1.0	15 ± 1.5
- Contralateral area	60 ± 5.9	14 ± 1.6	11 ± 0.8	19 ± 2.9
Main effect of time	F2,134 = 16.9	F3,161 = 56.4	F3,112 = 36.4	F2,119 = 4.3
Main effect of location	F3,65 = 35.3	F3,62 = 11.0	F3,43 = 11.4	F3,62 = 0.02
Time × location interaction	F9,195 = 24	F9,186 = 5.4	F9,129 = 4.8	F9,186 = 0.07
Reaction time latencies
Reaction times at D0 - Capsaicin area	392 ± 34 ms	850 ± 69 ms	900 ± 64 ms	560 ± 65 ms
- Border area	441 ± 44 ms	820 ± 42 ms	879 ± 54 ms	534 ± 43 ms
- Remote area	458 ± 47 ms	809 ± 47 ms	997 ± 77 ms	572 ± 52 ms
- Contralateral area	476 ± 119 ms	849 ± 79 ms	971 ± 143 ms	540 ± 68 ms
Main effect of time	F2,137 = 10.7	F2,147 = 4.1	F3,100 = 4.0	F3,173 = 4.9
Main effect of location	F3,65 = 5.8	F3,62 = 1.8	F3,43 = 2.5	F3,65 = 0.1
Time × location interaction	F9,192 = 20.6	F9,174 = 1.3	F9,121 = 2.9	F9,192 = 0.6