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. 2020 May 19;11:615. doi: 10.3389/fphar.2020.00615

Table 3.

Comparisons of the percentage of non-perceived stimuli, intensity ratings, and reaction times across time points.

Percentage of non-perceived stimuli D1 vs. D0 D3 vs. D0 D7 vs. D0
High-intensity heat (55°C) Capsaicin area T = −62.22 p < 0.0001*** T = −22.85 p = 0.0034** T = −3.176 p = 0.1198
Border area T = 1.986 p = 0.3279 T= 1.190 p = 0.5327 T = 1.190 p = 0.8423
Remote area T = 0.0000 p > 0.9999 T = 0.0047 p > 0.9999 T = −0.3905 p = 0.9722
Contralateral area T = 0.0000 p > 0.9999 T = 0.0000 p > 0.9999 T = 0.0000 p > 0.9999
Intermediate-intensity heat (44°C) Capsaicin area T = −76.66 p < 0.0001*** T = −62.99 p < 0.0001*** T = −15.00 p = 0.0217*
Border area T = −19.16 p = 0.0166* T = −12.51 p = 0.0018** T = −5.415 p = 0.2271
Remote area T = −9.165 p = 0.0356* T = −7.495 p = 0.0462* T = −7.510 p = 0.4401
Contralateral area T = −5.550 p = 0.5181 T = −5.550 p = 0.7567 T = 1.850 p = 0.9837
Low-intensity heat (38°C) Capsaicin area T = −68.57 p < 0.0001*** T = −70.24 p < 0.0001*** T = −30.72 p = 0.0038**
Border area T = −18.45 p = 0.0017** T = −14.88 p = 0.0193* T = −12.51 p = 0.4199
Remote area T = −14.29 p = 0.0001*** T = −11.31 p = 0.0176* T = −10.72 p = 0.0495*
Contralateral area T = −6.660 p > 0.9999 T = −6.660 p > 0.9999 T = −6.660 p > 0.9999
Cool (10°C) Capsaicin area T = −3.340 p = 0.3502 T = −2.675 p = 0.1159 T = −2.680 p = 0.6943
Border area T = 0.8400 p = 09220 T = −08300 p = 09715 T = 0.8300 p = 0.9245
Remote area T = 0.4200 p = 0.9927 T = −1.245 p = 0.9051 T = 1.250 p = 0.5325
Contralateral area T = 0.0000 p > 0.9999 T = 0.0000 p > 0.9999 T = 0.0000 p > 0.9999
Intensity of perception
High-intensity heat (55°C) Capsaicin area
Border area
T = 91.26 p < 0.0001***
T = −5.952 p = 0.6746
T = 78.94 p < 0.0001***
T = 12.85 p = 0.2631
T = 33.74 p = 0.0008***
T = 4.681 p = 09605
Remote area T = −2.614 p = 0.9508 T = 12.61 p = 0.2150 T = 1060 p = 05222
Contralateral area T = −1.383 p = 0.9963 T = −5.317 p = 0.8357 T = −7.700 p = 0.7554
Intermediate-intensity heat (44°C) Capsaicin area T = 92.76 p < 0.0001*** T = 89.72 p < 0.0001*** T = 59.54 p < 0.0001***
Border area T = 47.85 p < 0.0001*** T = 45.75 p < 0.0001*** T = 36.69 p = 0.0351*
Remote area T = 48.71 p < 0.0001*** T = 43.57 p = 0.0002*** T = 49.67 p < 0.0001***
Contralateral area T = 15.42 p = 0.8315 T = 34.45 p = 0.0791 T = 25.08 p = 0.6065
Low-intensity heat (38°C) Capsaicin area T = 93.32 p < 0.0001*** T = 93.21 p < 0.0001+++ T = 59.58 p < 0.0001***
Border area T = 50.93 p < 0.0001*** T = 50.50 p = 0.0003*** T = 39.06 p = 0.0694
Remote area T = 36.71 p = 0.0181* T = 48.48 p = 0.0012++ T = 40.16 p = 0.0020**
Contralateral area T = 0.4200 p > 0.9999 T = 16.64 p = 0.8014 T = 28.62 p = 0.1738
Cool (10°C) Capsaicin area T = −20.13 p = 0.7243 T = 7.175 p = 0.9183 T = 0.7500 p = 0.9999
Border area T = −16.81 p = 0.7130 T = 8.410 p = 0.6711 T = 1.845 p = 0.9979
Remote area T = −16.24 p = 0.7610 T = 7.850 p = 0.8231 T = −1.225 p = 0.9996
Contralateral area T = −24.72 p = 0.4252 T = −1.950 p = 0.9965 T = 5.683 p = 0.9411
Reaction times
High-intensity heat (55°C) Capsaicin area T = −516.5 p < 0.0001*** T = −411.7 p < 0.0001*** T = −122.2 p = 0.0125*
Border area T = 21.94 p = 0.6487 T = 5.295 p = 0.9960 T = −1586 p = 0.9997
Remote area T = 23.24 p = 0.6965 T = 11.71 p = 0.9195 T = 14.16 p = 0.9439
Contralateral area T = 37.77 p = 0.1368 T = 47.35 p = 0.3291 T = 70.93 p = 0.3571
Intermediate-intensity heat (44°C) Capsaicin area T = −132.5 p = 0.4135 T = −43.75 p = 0.8981 T = 60.28 p = 0.6444
Border area T = 11.38 p = 0.9889 T = 44.42 p = 0.6323 T = 77.17 p = 0.1427
Remote area T = 15.55 p = 0.9887 T = 49.08 p = 0.6701 T = 89.22 p = 0.1114
Contralateral area T = 85.43 p = 0.4508 T = 76.40 p = 0.1633 T = 78.95 p = 0.4221
Low-intensity heat (38°C) Capsaicin area T = −437.4 p = 0.0694 T = −1201 p = 0.7100 T = −132.2 p = 0.2049
Border area T = −104.4 p = 0.2112 T = −67.11 p = 0.6458 T = −23.36 p = 0.8870
Remote area T = 44.05 p = 0.8609 T = 108.2 p = 0.4350 T = 111.6 p = 0.2718
Contralateral area T = −11.00 p = 0.9997 T = 1.980 p > 0.9999 T = 34.76 p = 0.9839
Cool (10°C) Capsaicin area T = −28.17 p = 0.8682 T = 50.14 p = 0.4834 T = 80.92 p = 0.2891
Border area T = 3.148 p = 0.9993 T = 29.78 p = 0.7242 T = 47.99 p = 0.2396
Remote area T = 26.75 p = 0.4076 T = 54.79 p = 0.1856 T = 81.49 p = 0.1240
Contralateral area T = 27.95 p = 0.8004 T = 64.98 p = 0.0928 T = 32.98 p = 0.4593

The table reflects the differences in mean and corrected p-values (* indicates p ≤ 0.05, ** ≤ 0.01, and ***≤ 0.001).