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. 2020 May 19;11:324. doi: 10.3389/fendo.2020.00324

Table 1.

Bisphenols ranked according to the mean relative peak Ca2+ signal induced at 10 μM, i.e., the peak Ca2+ signal induced by the bisphenol at 10 μM divided by the peak Ca2+ signal induced by progesterone at 5 μM in the same experiment.

Rank Name CAS number Abbrevation Mean relative peak Ca2+ signal at 10 μM (in %) (n = 3) Chemical structure
Positive hits 1 Bisphenol G 127-54-8 BPG 109.02 graphic file with name fendo-11-00324-i0001.jpg
2 Bisphenol AF 1478-61-1 BPAF 57.95 graphic file with name fendo-11-00324-i0002.jpg
3 Bisphenol C 79-97-0 BPC 21.67 graphic file with name fendo-11-00324-i0003.jpg
4 Bisphenol A diglycidyl ether 1675-54-3 BADGE 14.79 graphic file with name fendo-11-00324-i0004.jpg
5 Bisphenol B 77-40-7 BPB 11.75 graphic file with name fendo-11-00324-i0005.jpg
6 Bisphenol BP 1844-01-5 BPBP 9.09 graphic file with name fendo-11-00324-i0006.jpg
Negative hits 7 Bisphenol E 2081-08-5 BPE 5.37 graphic file with name fendo-11-00324-i0007.jpg
8 Bisphenol F 620-92-8 BPF 5.09 graphic file with name fendo-11-00324-i0008.jpg
9 Bisphenol S 80-09-1 BPS 4.41 graphic file with name fendo-11-00324-i0009.jpg
10 Bisphenol A 80-05-7 BPA 1.44 graphic file with name fendo-11-00324-i0010.jpg

Based on their ability to induce Ca2+ signals, the bisphenols are categorized into “positive hits,” which induced mean relative peak Ca2+ signals above that of the negative controls (HTF+ with vehicle) ± 3 × SD (0.0 ± 3 × 2.3 = 6.9%) and “negative hits.” CAS number, abbreviation, and chemical structure are also listed in the table.