Table 3.
The most highly significantly DEGs in obese BC as compared with non-obese BC patients, ordered depending on LogFC.
| Gene symbol | Gene name | Gene type | LogFC | p-value | |
|---|---|---|---|---|---|
| 1 | ADCY1 | Adenylate cyclase type 1 | Coding | 5.52 | 0.0001 |
| 2 | ASPM | Abnormal spindle-like microcephaly-associated protein | Coding | 4.33 | <0.0001 |
| 3 | E2F7 | Transcription factor E2F7 | Coding | 4.18 | 0.0001 |
| 4 | GALNT9 | Polypeptide N-acetylgalactosaminyltransferase 9 | Coding | 4.10 | 0.0001 |
| 5 | MYH10 | Myosin-10 | Coding | 4.03 | <0.0001 |
| 6 | SEPT3 | Neuronal-specific septin-3 | Coding | 3.90 | 0.0001 |
| 7 | CDK1 | Cyclin-dependent kinase 1 | Coding | 3.84 | 0.0001 |
| 8 | AP001429.1 | LncRNA-AP001429.1 | Non-coding | 3.74 | <0.0001 |
| 9 | IGFBP2 | Insulin-like growth factor-binding protein 2 | Coding | 3.68 | 0.0001 |
| 10 | BUB1B | Mitotic checkpoint serine/threonine-protein kinase BUB1 beta | Coding | 3.50 | <0.0001 |
| 11 | CENPF | Centromere protein F | Coding | 3.49 | <0.0001 |
| 12 | OLFM4 | Olfactomedin-4 | Coding | 3.47 | <0.0001 |
| 13 | TOP2A | DNA topoisomerase 2-alpha | Coding | 3.44 | <0.0001 |
| 14 | TICRR | Treslin | Coding | 3.42 | 0.0001 |
| 15 | CEP55 | Centrosomal protein of 55 kDa | Coding | 3.17 | 0.0001 |
| 16 | UHRF1 | ubiquitin like with PHD and ring finger domains 1 | Coding | 3.17 | 0.0001 |
| 17 | SCN8A | Sodium channel protein type 8 subunit alpha | Coding | 3.08 | 0.0001 |
| 18 | SLCO4A1 | Solute carrier organic anion transporter family member 4A1 | Coding | 3.02 | <0.0001 |
| 19 | CD109 | CD109 antigen | Coding | 2.97 | 0.0001 |
| 20 | BRCA2 | Breast cancer type 2 susceptibility protein | Coding | 2.81 | 0.0001 |
| 21 | MYB | Transcriptional activator Myb | Coding | 2.74 | 0.0001 |
| 22 | MKI67 | Proliferation marker protein Ki-67 | Coding | 2.66 | 0.0001 |
| 23 | ARHGEF10 | Rho guanine nucleotide exchange factor 10 | Coding | 2.65 | <0.0001 |
| 24 | TIGD3 | Tigger transposable element-derived protein 3 | Coding | −0.95 | 0.0001 |
| 25 | TPST1 | Tyrosylprotein sulfotransferase 1,-like | Coding | −1.32 | <0.0001 |
| 26 | VSIG4 | V-set and immunoglobulin domain-containing protein 4 | Coding | −1.66 | <0.0001 |
| 27 | RNY1 | RNA, Ro-Associated Y1 | Non-coding | −2.24 | 0.0001 |
| 28 | IGLV1-47 | Immunoglobulin lambda variable 1-47 | Coding | −2.75 | <0.0001 |
| 29 | IGKV1D-16 | Immunoglobulin kappa variable 1D-16 | Coding | −2.77 | 0.0001 |
| 30 | IGHV6-1 | Immunoglobulin heavy variable 6-1 | Coding | −3.62 | <0.0001 |
| 31 | PGF | Placenta growth factor | Coding | −5.53 | <0.0001 |
LogFC rounded to two numbers after the decimal point. FC, Fold change.