Table 2.

Effects on hemodynamic integrity of anesthetics used in mouse fMRI.

Anesthetics are listed according to their classes: GABA_A agonists, including injectable drugs (red) and volatile ethers (yellow), α2AR agonists (green), and NMDA antagonists (blue). Vascular effects including vasodilation and vasoconstriction may impact on cerebral blood flow (CBF), intracranial pressure (ICP), or cerebral autoregulation (AutoReg). Drugs may further affect the cerebral metabolic rate of oxygen consumption (CMRO₂) and the regulation of the CO₂ metabolism (CO₂Reg). Effect: ↓ reduction; ↓↓ strong reduction; ↑ increase; ↑↑ strong increase;–no change. Based on Bittner et al. (2019).