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. 2020 May 19;8:463. doi: 10.3389/fbioe.2020.00463

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Copyright © 2020 Zheng, Tian, Gao, Yu, Xia, Feng, Dong, Wu and Sui.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Surface topography influences cell adhesion. (A,B) The relative mRNA levels of integrin α2 and vinculin in cell cultured on different titanium surfaces for 6 and 24 h. Statistical significance was determined by one-way ANOVA. Error bars represent SD (n = 3). *P < 0.05. **P < 0.01. ***P < 0.005. (C,D) Western blot analysis of integrin α2, vinculin, FAK and p-FAK in cell cultured on different titanium surfaces for 6 (C) and 24 h (D). Cells were cultured on different materials as indicated above.