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Integrin α2 overexpression activates PI3K-AKT signal pathway. (A) The relative mRNA levels of integrin α2 in scramble and integrin α2 overexpressed cell for 3 days. Statistical significance was determined by one-way ANOVA. Error bars represent SD (n = 3). ****P < 0.001. (B) Western blot analysis of integrin α2 in scramble and integrin α2 overexpressed cell. (C) Western blot analysis of PI3K, PIP2, PIP3, AKT, and p-AKT in scramble and integrin α2 overexpressed cell.
