Fig. 1.

The Morris water maze test confirmed that relatively high-intensity exercise improved learning and memory in obese mice. (A) Changes in platform arrival time (escape latency) for all groups during training session. (B) Probe test confirmed that relatively high-intensity exercise improved spatial memory on obese mice. (C) Mouse swimming path during probe testing confirmed by video tracking system. Data are presented as mean±standard deviation. HFD, high-fat diet; LIE, low-intensity exercise; MIE, middle intensity exercise; HIE, high-intensity exercise. *P<0.05.