Table II.
Demographics and clinical characteristics of all participants.
| Characteristics | All (n=134) | AD (n=72) | Control (n=62) | P-value |
|---|---|---|---|---|
| Age, years | 72.9±8.0 | 73.7±7.7 | 71.8±8.1 | 0.172a |
| Sex, female/male | 77/57 | 38/34 | 39/23 | 0.241b |
| Education, years | 5.0 (3.8–3.0) | 5.0 (4.8–3.0) | 6.0 (3.0–3.5) | 0.940c |
| MMSE | 16.5±8.2 | 13.7±6.7 | 27.2±2.1 | <0.001a |
| CDR | 0/1/2/3 (62/9/36/27) | 1/2/3 (9/36/27) | 0 (62) | – |
| Onset time, years | – | 3 (2–6.8) | – | – |
| Hypertension | 97 (72.4%) | 51 (70.8%) | 46 (74.2%) | 0.673b |
| FPG, mmol/l | 5.2 (4.7–3.2) | 5.3 (4.6–3.7) | 5.1 (4.8–3.7) | 0.564c |
| HbA1c, % | 6.76±1.86 | 7.09±2.1 | 6.3±1.38 | 0.132a |
| Blood lipid level, mmol/l | ||||
| TG | 0.99 (0.78–3.40) | 0.91 (0.71–3.21) | 1.12 (0.87–3.58) | 0.009c |
| TC | 4.48±1.13 | 4.14±0.99 | 4.89±1.16 | 0.001a |
| LDL-C | 2.44±0.79 | 2.33±0.74 | 2.58±0.83 | 0.125a |
| HDL-C | 1.38±0.45 | 1.28±0.42 | 1.50±0.45 | 0.016a |
| HCY, µmol/l | 20.9±7.2 | 21.0±7.9 | 20.6±4.35 | 0.852a |
| Hb (female), g/l | 120.6±14.1 | 117.9±15.5 | 124.1±11.6 | 0.194a |
| Hb (male), g/l | 135.2±16.3 | 130.9±17.5 | 142.4±11.2 | 0.032a |
| Abnormal thyroid hormone levels | 45 (33.6%) | 29 (40.2%) | 16 (26.0%) | 0.274b |
| Heart disease | 62 (46.3%) | 41 (57%) | 21 (33.9%) | 0.091b |
| Smoking status | 45 (33.6%) | 22 (30.5%) | 23 (37%) | 0.643b |
| Drinking status | 39 (29.1%) | 19 (26.4%) | 20 (32.3%) | 0.672b |
| History of anesthesia | 50 (37.3%) | 28 (38.9%) | 22 (35.5%) | 0.791b |
a
P-values were calculated by Student's t-test
b
P-values were calculated by χ2 test
c
P-values were calculated by Mann-Whitney U test; P<0.05 was considered to indicate a statistically significant difference. MMSE, Mini Mental State Examination; CDR, Clinical Dementia Rating Scale; FPG, fasting plasma glucose; HbA1c, hemoglobin A1c; TG, triglyceride; TC, total cholesterol; LDL-C, low-density lipoprotein cholesterol; HDL-C, high-density lipoprotein cholesterol; HCY, homocysteine; Hb, hemoglobin.