Table 3.
Response rates based on intention-to-treat between VCD and CTD groups.
| Response rate after 4 cycles | VCD (%) N = 117 | CTD (%) N = 194 | P |
|---|---|---|---|
| ≥Complete response | 20 (17.1) | 10 (5.1) | NS |
| ≥Very good partial response | 64 (54.7) | 83 (42.8) | 0.05 |
| ≥Partial response | 96 (82.1) | 153 (78.9) | NS |
| Minimum response | 5 (4.3) | 10 (5.2) | NS |
| Stable disease | 7 (6.0) | 7 (3.6) | NS |
| Progressive disease | 2 (1.7) | 6 (3.1) | NS |
| Not evaluated | 7 (6.0) | 18 (9.3) | NS |
VCD: velcade, cyclophosphamide, and dexamethasone; CTD: cyclophosphamide, thalidomide, and dexamethasone; ITT: intention-to-treat; NS: not significant.