Figure 2.
Effects of Dex on reducing the expression levels of inflammatory factors. Changes in (A) IL-6 and (B) MCP-1. Changes in the protein expression of (C) iNOS and (D) P53. Sepsis was achieved by CLP. Data are presented as the mean ± SEM. n=6 per group. *P<0.05 and **P<0.01. Dex, dexmedetomidine; CLP, cecal ligation and puncture; YOH, yohimbine hydrochloride; IL-6, interleukin 6; MCP-1, monocyte chemoattractant protein-1; iNOS, nitric oxide synthase; C, control.