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. 2019 Dec 11;26(6):636–649. doi: 10.1111/cns.13274

Figure 1.

Figure 1

Structures and brain/plasma ratios of (−)‐phenserine (PhenT) and its three primary active metabolites. Following its administration, PhenT undergoes N‐demethylation to generate (−)‐N1‐norphenserine, (−)‐N8‐norphenserine, and, ultimately, (−)‐N1,N8‐bisnorphenserine