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. 2020 May 19;7:256. doi: 10.3389/fvets.2020.00256

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Copyright © 2020 Wallace, Mather, Kara, Naicker, Mokoena, Pretorius, Nefefe, Thema and Babiuk.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) Temperatures of mock-vaccinated calves following challenge with the virulent LSDV_WB isolate. Increases in rectal temperatures indicative of pyrexia (>39.5°C) were observed in calf D1-4 and D1-5 at 8 and 4 dpc, respectively. Febrile responses lasted for 4 days in animal D1-5, while the temperature normalized the following day in animal D1-4. (B) Temperatures of calves vaccinated with LSD-RVF.mf following challenge with the virulent LSDV_WB isolate. Increases in rectal temperatures indicative of pyrexia were observed in all calves, except animal A1-5, at 1 dpc. Febrile responses (in the range of 39.6–40.3°C) lasted for a single day, with temperatures normalizing by the following day.