Table 3.
Diagnostic performance of each B-mode US features and elasticity parameters with optimal cutoff value on SWE for predicting malignancy
| Variable | Cutoff | Sensitivity (%) | Specificity (%) | PLR | NLR | AUC |
|---|---|---|---|---|---|---|
| Composition | Solid | 100 | 46.30 | 1.86 | 0 | 0.731 |
| Echogenicity | Hypoechogenic | 82.93 | 81.48 | 4.48 | 0.21 | 0.838 |
| Margin | Irregular | 80.49 | 79.63 | 3.95 | 0.25 | 0.801 |
| Shape | Taller than wide | 58.54 | 81.48 | 3.16 | 0.51 | 0.700 |
| Calcification | Presence | 73.17 | 85.19 | 4.94 | 0.31 | 0.808 |
| US category | High suspicion | 95.12 | 85.19 | 6.42 | 0.06 | 0.913 |
| Emean | >54.9 | 36.59 | 87.04 | 2.82 | 0.73 | 0.631 |
| Emax | >47.1 | 53.66 | 70.37 | 1.81 | 0.66 | 0.633 |
| Emin | >40.4 | 31.71 | 88.89 | 2.85 | 0.77 | 0.613 |
| Eratio | >1.94 | 92.68 | 29.63 | 1.32 | 0.25 | 0.609 |
US, ultrasound; SWE, shear wave elastography; PLR, positive likelihood ratio; NLR, negative likelihood ratio; AUC, area under the receiver operating characteristic curve; Emean, mean value for a 2-mm diameter region of interest (ROI) placed in the stiffest region; Emax, maximum pixel value for a ROI; Emin, minimum pixel value for a ROI; Eratio, the ratios of mean stiffness for the lesion-to-normal parenchyma.