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In vitro activity profiles of DAMGO, DALDA, [Dmt1]DALDA, and KGOP01 to the human MOR (hMOR). (A) Binding of tested peptides to the MOR was determined in competitive radioligand binding assays using CHO-hMOR cell membranes. (B) Stimulation of [35S]GTPγS binding by tested peptides was determined in the [35S]GTPγS binding assay using CHO-hMOR cell membranes. Values are expressed as the mean ± SEM (n = 3–4 independent experiments).
