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. 2020 May 8;25(9):2220. doi: 10.3390/molecules25092220

Table 1.

Thermodynamic constants measured by surface plasmon resonance (SPR) for the interaction between the tested compounds and immobilized Hsp90α.

Compound KD (nM)a
1b 51.0 ± 2.9
4 NBc
5 NB
17-AAG 360.0 ± 21.9

a: Results were given as the mean ± standard deviation; b: named HAA2020 in this study; c: No binding.