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. 2020 May 20;13:4397–4409. doi: 10.2147/OTT.S245554

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© 2020 Chen et al.

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ZNF667-AS1 is poorly expressed in NPC clinical samples and cells. (A) The heatmap of NPC-related GSE12452 microarray dataset, the abscissa represents the sample number, the ordinate represents the differentially expressed lncRNAs, the histogram in the upper right is the color scale, and each rectangle in the figure corresponds to a sample expression value. (B) RT-qPCR used to detect the expression of ZNF667-AS1 in tumor and adjacent tissues (n = 36). *p < 0.05 vs adjacent tissues. (C) RT-qPCR used to detect the expression of ZNF667-AS1 in NPC cells and nasopharyngeal epithelial cells. *p < 0.05 vs NP69 cells. Data are expressed as mean ± standard deviation. Paired t test is used for comparison of two groups. One-way analysis of variance is used for comparison among multiple groups.

Abbreviations: ZNF667-AS1, zinc finger protein 667-antisense RNA 1; NPC, nasopharyngeal carcinoma; lncRNA; long noncoding RNA; RT-qPCR, reverse transcription quantitative polymerase chain reaction.