Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Apr 28;25(9):2058. doi: 10.3390/molecules25092058

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Proliferation effect of Naphthoquinone amino acid derivatives was evaluated in HPV positive cancer cell lines derived from cervix and a non-tumorigenic HPV negative cell line. (A) HaCaT HPV negative cell line cells were treated with 6.25, 12.5, 25, 50, 100 and 200 μM of naphthoquinone amino acid derivatives to assay proliferation rate at 72 h post-treatment. (B) SiHa HPV 16 positive cancer cells were treated with 6.25, 12.5, 25, 50, 100 and 200 μM of naphthoquinone amino acid derivatives to assay proliferation rate at 72 h post-treatment. (C) CaLo HPV 18 positive cancer cells were treated with 6.25, 12.5, 25, 50, 100 and 200 μM of naphthoquinone amino acid derivatives to assay proliferation rate at 72 h post-treatment. (D) C33-A HPV negative cancer cells were treated with 6.25, 12.5, 25, 50, 100 and 200 μM of naphthoquinone amino acid derivatives to assay proliferation rate at 72 h post-treatment. Cells treated with 0.1% of DMSO were used as Control. * represents statistically significant p < 0.05 value.

Proliferation effect of Naphthoquinone amino acid derivatives was evaluated in HPV positive cancer cell lines derived from cervix and a non-tumorigenic HPV negative cell line. (A) HaCaT HPV negative cell line cells were treated with 6.25, 12.5, 25, 50, 100 and 200 μM of naphthoquinone amino acid derivatives to assay proliferation rate at 72 h post-treatment. (B) SiHa HPV 16 positive cancer cells were treated with 6.25, 12.5, 25, 50, 100 and 200 μM of naphthoquinone amino acid derivatives to assay proliferation rate at 72 h post-treatment. (C) CaLo HPV 18 positive cancer cells were treated with 6.25, 12.5, 25, 50, 100 and 200 μM of naphthoquinone amino acid derivatives to assay proliferation rate at 72 h post-treatment. (D) C33-A HPV negative cancer cells were treated with 6.25, 12.5, 25, 50, 100 and 200 μM of naphthoquinone amino acid derivatives to assay proliferation rate at 72 h post-treatment. Cells treated with 0.1% of DMSO were used as Control. * represents statistically significant p < 0.05 value.