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. 2020 Apr 27;25(9):2042. doi: 10.3390/molecules25092042

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Effect of genistin and genistein on mRNA levels of lipogenic-related factors in 3T3-L1 adipocytes. 3T3-L1 cells were completely differentiated in the MDI media in the presence of 25, 50, or 100 μM genistin or genistein during the differentiation process. The mRNA expression of lipogenic factors, including (A) ACL, (B) ACC1, and (C) FAS was evaluated. All data were expressed as fold changes in expression relative to that in the control, untreated adipocytes (n ≥ 3, ^### p < 0.001 vs. Pre (preadipocyte) group; * p < 0.05, *** p < 0.001 vs. Con (control, adipocyte) group; one-way ANOVA with the Tukey’s post-hoc test). ACL, ATP citrate lyase; ACC1, acetyl-CoA carboxylase 1; FAS, fatty acid synthase.