Table 4.
Pharmacokinetic data for 76 from phase 0 clinical studies.
| Dose (mg) | Tmax (h) | Cmax (ng/mL) | t1/2 (h) | Oral Bioavailability (%) |
|---|---|---|---|---|
| 20 * | 0.3 | 1144 | - | - |
| 50 | 2.2 | 303 | 14 | 56 |
| 100 | 2.5 | 311 | 21 | 33 |
* Intravenous.
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