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. 2020 Apr 27;25(9):2031. doi: 10.3390/molecules25092031

Table 6.

Inhibitory effect of compounds 6a–h, 9a, and 9e on CDK2 and CDK9 at a single-dose of 20 µM.

Comp. % Enzyme Inhibitory Activity
CDK2 CDK9
6a 78 20
6b 48 7
6c 57 11
6d 85 32
6e 68 18
6f 50 8
6g 14 4
6h 67 10
9a 41 13
9e 5 9
Staurosporine 99 98