Table 1.
IC50 values of the bioassays of the compounds isolated from Nigella sativa.
| Compound Number | DPPH Assay | ABTS Assay | α-Glucosidase Assay | PTP1B Assay |
|---|---|---|---|---|
| 1 | Nd | Nd | 217.5 ± 2.6 | Nd |
| 2 | Nd | Nd | 256.7 ± 3.7 | Nd |
| 3 | Nd | Nd | Nd | Nd |
| 4 | Nd | Nd | 254.2 ± 4.5 | Nd |
| 5 | 71.0 ± 0.5 | 139.2 ± 0.5 | 335.3 ± 0.2 | Nd |
| 6 | 32.7 ± 0.1 | 95.18 ± 0.9 | 257.8 ± 0.8 | Nd |
| 7 | Nd | Nd | 276.2 ± 2.1 | Nd |
| 8 | 35.5 ± 0.5 | 98.8 ± 0.5 | 274.1 ± 0.3 | Nd |
| 9 | 197.8 ± 2.7 | 247 ± 2.7 | 360.0 ± 0.3 | Nd |
| 10 | Nd | Nd | 214.5 ± 0.0 | Nd |
| 11 | 39.6 ± 0.5 | 129.0 ± 0.5 | 331.9 ± 1.6 | Nd |
| 12 | Nd | Nd | Nt | 91.3 ± 2.5 |
| 13 | Nd | Nd | Nt | Nd |
| 14 | Nd | Nd | Nt | Nd |
| 15 | Nd | Nd | Nt | Nd |
| Ascorbic acid | 51.7 ± 0.1 | 82.9 ± 2 | Nt | Nt |
| Trolox | 59.4 ± 0.9 | 96.2 ± 1.5 | Nt | Nt |
| Acarbose | Nt | Nt | 127.9 ± 2.0 | Nt |
| Ursolic acid | Nt | Nt | Nt | 0.8 ± 1.4 |
The values are presented as the mean of three determination ± standard deviation. Nt (not tested), Nd (not detected). Ascorbic acid and Trolox were used as a positive control in the DPPH and ABTS assays. Acarbose and ursolic acid were used as positive controls in the α-glucosidase assay and PTP1B assay, respectively.