Table 4.
IC50 values (mean ± SD, μg/mL) of MGEOs 1 to 3 for cell lines after 48 h exposure to different MGEO concentrations.
| Cell Lines | IC50 μg/mL | |||
|---|---|---|---|---|
| MGEO-1 (Wild) |
MGEO-2 (Wild) |
MGEO-3 (Cultivated) |
Doxorubicin * | |
| PANC-1 | 14.76 ± 2.68 | 18.05 ± 3.72 | 46.87 ± 3.70 | 26.48 ± 2.16 |
| MCF-7 | 47.45 ± 1.45 | 39.52 ± 6.85 | 38.69 ± 4.33 | 20.25 ± 0.41 |
| MDA-MB-231 | 23.08 ± 0.55 | 26.55 ± 0.16 | 12.40 ± 0.39 | 19.33 ± 0.50 |
| PC3 | 15.3 ± 0.29 | 30.67 ± 5.72 | 19.54 ± 0.09 | 6.35 ± 0.38 |
| CaCo-2 | 31.74 ± 5.84 | 49.91 ± 0.40 | 47.60 ± 3.72 | 10.25 ± 0.26 |
| HeLa | 20.11 ± 4.15 | 18.81 ± 0.73 | 7.621 ± 1.91 | 2.14 ± 0.26 |
| 253J-BV | 15.96 ± 1.08 | 10.82 ± 1.25 | 12.14 ± 1.93 | 2.50 ± 1.30 |
| A549 | 7.02 ± 1.94 | 5.77 ± 1.65 | 19.93 ± 1.23 | 5.57 ± 1.09 |
| RAW264.7 | 7.62 ± 0.51 | 9.20 ± 2.64 | 5.84 ± 0.68 | 1.23 ± 0.53 |
| SK-MEL-30 | 5.25 ± 0.33 | 5.25 ± 0.81 | 13.31 ± 2.53 | 2.09 ± 0.18 |
| U87MG | 11.71 ± 2.74 | 6.12 ± 1.49 | 23.42 ± 3.21 | 6.38 ± 1.05 |
| HepG2 | 25.19 ± 2.51 | 44.83 ± 1.42 | 47.47 ± 2.54 | 5.63 ± 0.07 |
| HEK293 | 15.74 ± 0.08 | 17.83 ± 3.00 | 17.66 ± 1.58 | 1.19 ± 0.17 |
* Positive control.