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Activities of apratoxin-related analogues, apratoxins S4 (50), S7 (51)–S9 (53) on viability of HCT116 cell and secretion of VEGF-A (IC50 nM).
| Apratoxin | HCT116 | VEGF-A Secretion |
|---|---|---|
| S4 (50) | 1.43 | 0.32 |
| S7 (51) | 1.25 | 0.30 |
| S8 (52) | 1.99 | 0.47 |
| S9 (53) | 0.69 | 0.12 |
