Figure 3:
Comparison of predicted complexes against gold standard CORUM (version 2.0). Figure shows all predicted complexes (blue) across three different categories as a function of complex size. The categories are (1) identical match to complex in CORUM (gray), (2) strict subset to a complex in CORUM (yellow), and (3) potentially novel complex (orange). (A) Figure shows predicted complexes using Algorithm 1 for threshold t = 0.87 selected from top 0.02% of high-scoring proteins pairs. (B) Figure shows predicted refined complexes using Algorithm 2 with t′ = 0.85 on top 0.02% high-scoring proteins pairs shown in (A).