Table 2:
Summary of predicted protein complexes that are present in the latest CORUM release (version 3.0) but were not used for training. For each predicted complex, we provide the complex name, predicted member proteins, complex score and top 3 GO functional annotations from g:Profiler along with corresponding p-value.
| Complex name | Predicted complex members | Complex score | Top 3 GO annotations (p-value) |
|---|---|---|---|
| CCT complex | CCT2, CCT3, CCT4, CCT5, CCT7, CT8, CCT6A |
0.94 | Chaperonin-containing T-complex (2.2E-22) Regulation of protein localization to Cajal body (8.4E-22) Positive regulation of protein localization to Cajal body (8.4E-22) |
| ILK-LIMS1-PARVA complex | ILK, LIMS1, PARVA, RSU1 | 0.87 | Focal adhesion (5.1E-5) Cell-substrate adhesion (5.1E-5) Cell-substrate adherens junction (5.2E-5) |
| Respiratory chain complex I | NDUFA7, NDUFA8, NDUFA9, NDUFA10, NDUFB1, NDUFB4, NDUFB8, NDUFS1, NDUFS2, NDUFS3, NDUFV1, NDUFS4, NDUFS8, NDUFV2, NDUFA12 |
0.60 | NADH dehydrogenase (ubiquinone) activity (1.4E-39) NADH dehydrogenase (quinone) activity (1.4E-39) NADH dehydrogenase activity (2.3E-39) |