Table III.
Characteristics of children 2-18 years old with AOM who received first-line antibiotics compared with those who received non-first-line antibiotics at DH Medical Center, January to December 2018
| Characteristics | First-line antibiotics (n = 752) | Non-first-line antibiotics (n = 174) | P value* |
|---|---|---|---|
| Age (years) | .03 | ||
| 2-5 | 443 (58.9) | 94 (54.0) | |
| 6-10 | 214 (28.5) | 44 (25.3) | |
| >10 | 95 (12.6) | 36 (20.7) | |
| Female | 376 (50.0) | 74 (42.5) | .08 |
| Non-white/other race | 245 (32.6) | 53 (30.5) | .59 |
| Hispanic | 549 (73.0) | 127 (73.0) | .99 |
| Private insurance | 66 (8.8) | 27 (15.5) | .008 |
| Location | .93 | ||
| Pediatric clinic | 345 (45.9) | 79 (45.4) | |
| Nonpediatric clinic | 158 (21.0) | 35 (20.1) | |
| Emergency/urgent care | 249 (33.1) | 60 (34.5) | |
| SNAPs | 35 (4.7) | 7 (4.0) | .72 |
| Penicillin allergy | 4 (0.5) | 7 (4.0) | .001 |
| Received ≥1 dose PCV13 | 603 (80.2) | 126 (72.4) | .02 |
| Received ≥2 doses any PCV | 682 (73.7) | 151 (86.8) | .12 |
| Smoke exposure | 103 (13.7) | 29 (16.7) | .31 |
| Hospitalized in prior year | 23 (3.1) | 2 (1.2) | .20 |
| ≥3 Sick visits in prior year | 277 (36.8) | 69 (39.7) | .49 |
| Bilateral infection | 146 (19.4) | 47 (27.0) | .03 |
| Failed OTC medication trial | 52 (6.9) | 11 (6.3) | .78 |
| Fever† | 348 (46.3) | 73 (42.0) | .30 |
|
Multivariate logistic model for first-line vs non-first-line antibiotics‡ | |||
| Final model | |||
| Age, years | |||
| 2-5 | 0.55 (0.29-1.05) | .05 | |
| 6-10 | 0.52 (0.27-0.99) | .07 | |
| >10 | Referent | ||
| Female | 0.70 (0.50-0.99) | .04 | |
| Non-white/other race | 0.94 (0.64-1.38) | .77 | |
| Hispanic | 1.03 (0.68-1.54) | .90 | |
| Private insurance | 1.89 (1.14-3.14) | .01 | |
| Penicillin allergy | 8.13 (2.3-28.7) | .001 | |
| Received ≥1 dose PCV13 | 1.09 (0.63-1.89) | .76 | |
| Bilateral infection | 1.56 (1.06-2.31) | .02 | |
OTC, over-the-counter; PCV, pneumococcal conjugate vaccine.
Values that are statistically significant are in bold.
Values are number (%) or aOR (Wald 95% CI).
*
Calculated using 2-sided χ2 or Fisher exact test with significance defined as P < .05.
†
Fever subjectively reported by parents or documented as ≥100.4°F.
‡
Factors with P < .1 on univariate analysis were included in the logistic regression model along with race and ethnicity regardless of significance.