Table 2.
Molar ratios of lipids to apoA-I in the four HDL subfractions. Data in the first row are mean lipid to apoA-I molar ratios +/− SD. The second row of each analyte shows the significance values from a post-hoc pairwise comparison versus the E-CIII- fraction. The third row of each analyte shows the proportion of each lipid in that fraction as a percentage of the total mass of such lipid in HDL. The last row shows the significance value from a global one-way ANOVA for the analysis of lipid to apoA-I molar ratios by subfractions
| E-CIII- | E + CIII- | E-CIII+ | E + CIII+ | ||
|---|---|---|---|---|---|
| Triglycerides | to apoA-I molar ratio | 0.47 +/− 0.22 | 1.09 +/− 1.41 | 2.73 +/− 3.48 | 2.41 +/− 1.87 |
| p-value versus E-CIII- | – | 0.88 | 0.035 | 0.09 | |
| % of total mass in HDL | 25.2% | 17.2% | 29.8% | 27.7% | |
| p-value from ANOVA | 0.01 | ||||
| Cholesterol | to apoA-I molar ratio | 26.6 +/− 18.7 | 51.5 +/− 68.4 | 48.1 +/− 32 | 52.6 +/− 38.1 |
| p-value versus E-CIII- | – | 0.43 | 0.55 | 0.39 | |
| % of total mass in HDL | 40.7% | 22.5% | 20.8% | 15.8% | |
| p-value from ANOVA | 0.26 | ||||
| Phosphatidylcholine | to apoA-I molar ratio | 109.2 +/− 69.3 | 317.6 +/− 367.7 | 455.7 +/− 547.3 | 488.2 +/− 669.2 |
| p-value versus E-CIII- | – | 0.65 | 0.21 | 0.15 | |
| % of total mass in HDL | 27.1% | 27.0% | 26.0% | 19.7% | |
| p-value from ANOVA | 0.088 | ||||
| Cholesterol esters | to apoA-I molar ratio | 14.6 +/− 16 | 23 +/− 29.9 | 16.3 +/− 37.9 | 30 +/− 103 |
| p-value versus E-CIII- | – | 0.98 | 0.99 | 0.89 | |
| % of total mass in HDL | 48.6% | 28.8% | 12.3% | 10.1% | |
| p-value from ANOVA | 0.86 | ||||