Table 2.
Univariate and multivariate Cox regression analysis for cancer specific survival in patients ESCC with stage T1-3N0M0 (Cox regression’s method is Forward: LR)
| Characteristics | Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|---|
| HR | 95% CI | P value | HR | 95% CI | P value | |
| Gender (male vs. female) | 0.722 | 0.456–1.141 | 0.163 | |||
| Age (continuous) | 1.020 | 0.997–1.043 | 0.082 | |||
| Smoking history (no vs. yes) | 1.608 | 1.059–2.443 | 0.036 | – | – | 0.283 |
| Drinking history (no vs. yes) | 1.681 | 1.150–2.459 | 0.007 | 1.878 | 1.275–2.765 | 0.001 |
| Primary tumor location | ||||||
| Upper (reference) | 1 | – | – | |||
| Middle | 0.728 | 0.334–1.585 | 0.424 | |||
| Lower | 1.023 | 0.688–1.522 | 0.910 | |||
| pT stage (T1 vs. T2 vs. T3) | 1.445 | 1.102–1.894 | 0.008 | 1.551 | 1.167–2.061 | 0.002 |
| SCC-Ag (continuous) | 1.227 | 1.105–1.361 | < 0.001 | 1.200 | 1.083–1.330 | 0.001 |
| Albumin (continuous) | 0.939 | 0.889–0.991 | 0.022 | 0.945 | 0.896–0.997 | 0.038 |
| LNs (continuous) | 0.984 | 0.969–0.999 | 0.040 | 0.982 | 0.967–0.997 | 0.020 |
| Tumor length (continuous) | 1.070 | 0.960–1.194 | 0.222 | |||
| Anastomotic leakage (no vs. yes) | 1.078 | 0.579–2.009 | 0.812 | |||
| Chylothorax (no vs. yes) | 1.066 | 0.149–7.640 | 0.949 | |||
| Respiratory complications (no vs. yes) | 0.880 | 0.324–2.389 | 0.803 | |||
| Cardiovascular complications (no vs. yes) | 1.118 | 0.276–4.529 | 0.876 | |||
The factors in the univariate analyses with P value less than 0.05 would be took in account into multivariate analyses. LNs the number of lymph nodes removed in surgery, HR hazard ratio, CI confident interval