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. 2020 May 25;20:209. doi: 10.1186/s12883-020-01760-x

Fig. 2.

Fig. 2

a-c. Median Difference in Each Cytokine Over Time from Time Point 1 to Time Point 2. Note. Time point 1 is <8 h after injury. Time point 2 is 24 h after time point 1. Mean difference = (each participant’s cytokine concentration at time point 2) - (each participant’s concentration level at time point 1). Mann Whitney U tests were conducted to determine if there were differences in the mean change variable between these groups. a. IL-6, b. IL-10, and c. TNFα. IL-6 was significantly different in the concussed group as compared to the healthy control at p<0.001