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. 2020 May 25;17:166. doi: 10.1186/s12974-020-01836-y

Fig. 4.

Fig. 4

Effect of DHLA on ROS/NLRP3/caspase-1/IL-1β signaling pathway in rats. a Representative Western blot bands in the hippocampal region. bd Statistical graphs of relative protein expression of NLRP3 (b), caspase-1 (c), and IL-1β (d). e ROS expression in the hippocampal. The data were expressed as means ± SEM (n = 6). ***P < 0.001; ****P < 0.0001 versus the control group. #P < 0.05; ##P < 0.01; ###P < 0.001 versus the LPS group. The Shapiro-Wilk test results showed that all the data are normally distributed (p > 0.05)