FIG. 5.

Transforming Research and Clinical Knowledge in Traumatic Brain Injury (TRACK-TBI) Pilot subjects classified into phenotypes demonstrate similar injury profiles and Extended Glasgow Outcome Scale (GOS-E) outcomes as Citicoline Brain Injury Treatment Trial (COBRIT) phenotype subjects. (A) T-distributed stochastic neighbor embedding (T-SNE) projection of the original COBRIT subject phenotypes (COBRIT Phen. A, Phen. B, Phen. C) with the addition of TRACK-TBI Pilot subjects given phenotype assignments by a K-nearest neighbors (K-NN) classifier (TRACK-TBI Phen. A, Phen. B, Phen. C). TRACK-TBI phenotype extended GOS-E scores at (B) 90 days and (C) 180 days post-injury significance was computed using the Kruskal–Wallis test with Holm's correction for multiple comparisons (asterisks represent p values: **p < 0.01, p > 0.05 n.s.). Color image is available online.